Monosomy 21 is a genetic condition in which an individual is missing one copy of chromosome 21 in their cells, instead of the usual two copies. This condition can result in a range of developmental and physical abnormalities, including intellectual disability, delayed growth and development, and distinctive facial features. Monosomy 21 is a rare condition and can occur as a result of a random error during the formation of reproductive cells or during early fetal development. It is also known as partial monosomy 21 or 21q deletion syndrome. **

Trisomy and monosomy can be lethal because they result in an imbalance of genetic material in an individual. Trisomy is the presence of an extra chromosome, while monosomy is the absence of a chromosome. This imbalance can disrupt normal development and lead to severe physical and intellectual disabilities, as well as organ malformations. In many cases, the body is unable to cope with these abnormalities, resulting in miscarriage or early death. **

Trisomy and monosomy can be deadly because they result in an abnormal number of chromosomes in the cells, disrupting the normal genetic balance. This imbalance can lead to developmental abnormalities, organ malformations, and other serious health issues. The body may not be able to function properly with these genetic abnormalities, leading to severe complications and potentially fatal outcomes. **

Tandoori Rogan Josh is a popular Indian dish made with marinated and grilled meat, typically lamb, in a rich and flavorful sauce made with yogurt, tomatoes, and various spices such as cumin, coriander, and garam masala. Tikka Masala is a dish made with marinated and grilled meat, usually chicken, in a creamy and spiced tomato sauce. Both dishes are known for their bold and aromatic flavors and are often served with rice or naan bread. **

Monosomy or trisomy of chromosomes 1 to 15 in newborns is extremely rare because these chromosomal abnormalities are typically not compatible with life. The loss or gain of genetic material on these chromosomes can lead to severe developmental abnormalities and miscarriages during pregnancy. Most cases of monosomy or trisomy involving these chromosomes result in early pregnancy loss rather than live births. Additionally, the body's natural mechanisms for quality control during cell division help to prevent the inheritance of these chromosomal abnormalities in newborns. **

Apple chutney is typically eaten as a condiment or accompaniment to a variety of dishes. It can be enjoyed with savory foods such as grilled meats, curries, and cheese, as well as with sweet dishes like desserts and pastries. The sweet and tangy flavor of apple chutney makes it a versatile and delicious addition to many different types of meals. **

To make Tandoori, start by marinating the main ingredient (such as chicken, fish, or paneer) in a mixture of yogurt, lemon juice, ginger, garlic, and a blend of spices including cumin, coriander, turmeric, and garam masala. Let the marinated ingredient sit for at least a few hours, or ideally overnight, to allow the flavors to penetrate. Then, cook the marinated ingredient in a tandoor oven, which is a cylindrical clay oven that reaches high temperatures, giving the dish its signature charred and smoky flavor. If you don't have a tandoor oven, you can also grill or bake the marinated ingredient to achieve a similar result. Serve the Tandoori hot, garnished with fresh cilantro and a squeeze of lemon juice. **

Tandoori spice mix can be found in most grocery stores in the spice aisle. It can also be purchased online from various retailers. Additionally, some specialty Indian grocery stores may carry a wider variety of Tandoori spice mixes, including different brands and variations. If you prefer a specific blend or want to explore different options, it's worth checking out different stores or online sources to find the Tandoori spice mix that best suits your taste preferences. **